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American Journal of PharmTech Research

Keyword

LDH

Explore 2 research publications tagged with this keyword

2Publications
9Authors
2Years

Publications Tagged with "LDH"

2 publications found

2014

1 publication

Effect of Taurine on Cytotoxic Markers In 7, 12- DimethylBenz (A) Anthracene Induced Mammary Carcinoma In Experimental Female Sprague-Dawley Rats

Vanitha Kalappan et al.
4/1/2014

Breast cancer comprises a diverse collection of diseases rather than a single homogeneous disease. Both preclinical and clinical research now commonly target specific subgroups of breast cancer with the aim of identifying biological markers or genetic phenotypes, and to reveal subgroup-specific therapeutic targets or indicators of prognosis. Since genetics is believed to account for only 10% of the reported cases, the environmental factors including diet are thought to play a significant role in predisposing breast cancer. The present study was aimed to evaluate the chemotherapeutic potential of taurine in 7, 12-dimethyl Benz (a) anthracene (DMBA) induced mammary carcinoma in rats. Oral treatment of taurine (100 mg/kg BW) to breast tumor bearing rats daily for ten to fifteen weeks was found to be effective against DMBA induced mammary gland carcinogenesis in female Sprague Dawley rats. The increased activities of 5′-ND, GGT and LDH in tissue of control and experimental breast cancer rats were significantly (p 

2013

1 publication

Effect of Aluminium Chloride on Testicular Marker Enzyme in Rat and the Effect of Vitamin-E

M.Tiroumavalavane et al.
6/1/2013

To investigate the effect of Aluminium chloride on the activities of testicular enzymes in rat. Forty male Albino rats were divided into four groups (n=10). Treatment was given for a period of 45 days daily. Group-I Control given only distilled water, Group-II treated with aluminium chloride 50 mg/Kg body wt. Group-III treated with Vitamin E 20mg/Kg body weight. Group-IV treated with aluminium chloride+ Vitamin-E. The animals were sacrificed after 24 hours duration. Biochemical studies were observed in testis. Marker enzymes ALP, ACP and LDH, SDH activities were decreased significantly with control. Lipid peroxidation was increased significantly in aluminium chloride treated rats. The administration of AlCl3+Vit E shows protective effect from the toxicity.

Keyword Statistics
Total Publications:2
Years Active:2
Latest Publication:2014
Contributing Authors:9
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