Ginger

The present research work is mainly concerned with the natural compounds that are obtained from traditional medicinal plants. There are number of natural compounds have been available in the nature. Some natural compounds are very useful to human being and have life potential to save human from many uncurable disease. Keeping view in the mind the research is focused to extract and isolate antioxidant, anti-inflammatory, anticancer, antihyperlipidemic, antidiabetic, antiulcer activities containing compounds are studied. The major natural compounds is ginger,   The ginger is obtained from rhizomes of zingiber officinale, and useful anti rhuematic and pungent and spicy contains gingerol and shogaol as active principles. All components are isolated from the concerned extracts. The extraction   of all plants are based on successive solvent extraction method for all drugs.The constituents are confirmed by structure elucidation. The structure of each compounds are intrepreted by different spectral techniques like Infrared spectrum, nuclear magnetic spectrum (hydrogen anc carbon thirteen spectra) and mass spectroscopy for molecular  formula and molecular weight of the unknown compounds.  The biological evaluation of each compound is performed separately. For antioxidant activity DPPH method is used. & the immunomodulatory activity

Diabetic mellitus goes with metabolic disorders involving hyperglycaemia and lipid disorders. The study investigated the activity of aqueous ginger extract on the glucose level and lipid profile of cholesterol-fed diabetic rats.  The rats were randomly distributed into four groups of 5 rats per group. Group A (control) were placed on normal rat feed. Diabetes was induced in groups B, C, and D by intraperitoneal administration of one dose of alloxan monohydrate (150mg/kg/bwt) and fed diet mixed with 1% cholesterol. The rats in groups C and D were orally administered with 250 and 500mg/kg/bwt of ginger extract respectively for 14 days. Biochemical parameters were analysed by standard methods. A significant decrease (P0.05). There was a statistical increase in the serum triacylglycerol level in group B compared to group A (P

It’s well established that oxygen is essential for survival and energy generation in all-living organisms and ~5% of its inhaled part is converted into free radicals (either ROS or RNS) as a by-product of aerobic metabolism. Free radicals are also generated on exposure to sun light, X-rays, O3, tobacco smoke, automobile exhaust, environmental pollutants, and several other physiological processes. These reactive species damage NAs, proteins, lipids, carbohydrate. that consequently affects the immune functions causing degenerative ailments. The initiation steps of oxygen induced oxidation require removal of H-atom which gets accelerated by the presence of certain metals such as Fe and Cu leading to formation of singlet oxygen. In a normal cell there is an appropriate balance between pro-oxidant and antioxidants. Increase in level of pro-oxidant as compared in antioxidant creates oxidative stress. Epidemiological studies provide convincing evidence that a diet rich in antioxidants is associated with a lower incidence of degenerative diseases. Fruits, vegetables and beverages( fruit juices, black-lemon-T, coffee, cocoa, beer & wine) are the potent sources of dietary polyphenols. People relying upon consuming traditional diets rich in soy and tea rarely bear breast, uterus and prostate cancer. Recent advances in biochemistry and molecular biology techniques providing tools for studying the antioxidant enzymes and for elucidating the mechanisms of the actions of antioxidants has been delineated in this manuscript. Keywords: Aloe Vera, Anti-oxidants, Curry plant, Phytochemicals, Cancerous maladies: Beer, Ginger, Pepper, Coconut, Tea, Tomato