glucose

Diabetic mellitus goes with metabolic disorders involving hyperglycaemia and lipid disorders. The study investigated the activity of aqueous ginger extract on the glucose level and lipid profile of cholesterol-fed diabetic rats.  The rats were randomly distributed into four groups of 5 rats per group. Group A (control) were placed on normal rat feed. Diabetes was induced in groups B, C, and D by intraperitoneal administration of one dose of alloxan monohydrate (150mg/kg/bwt) and fed diet mixed with 1% cholesterol. The rats in groups C and D were orally administered with 250 and 500mg/kg/bwt of ginger extract respectively for 14 days. Biochemical parameters were analysed by standard methods. A significant decrease (P0.05). There was a statistical increase in the serum triacylglycerol level in group B compared to group A (P

This study evaluates antihyperglycemic and lipid lowering activity of Caralluma fimbriata in dexamethasone induced diabetic rats. Serum glucose and lipid lowering activity of Caralluma fimbriata was tested at dose of 50 mg/kg and 100 mg/kg per oral route against dexamethasone induced hyperlipidemia and hyperglycemia in Spraugue-Dawley (SD) rats. On day 11, blood was collected for the estimation of serum glucose and lipids. Caralluma fimbrita in both the doses significantly decreased Serum glucose, total cholesterol, triglyceride and LDL as compared to dexamethasone only group (P