Novelanti-Psoriatic topical herbal gel containing cassiatora seeds extract

Herbal medicine has become an integral part of standard healthcare based on combination of traditional usage and on-going scientific research. Gel is a semisolid system consisting of dispersion made up of either small inorganic particles or large organic molecules enclosing an interpenetrated liquid. The inorganic particles form a three dimensional structure. The gel formulation was designed by using ethanolic extract of Cassia tora seeds and evaluated for various physiological measurements; preparation involved various concentration combinations of Carbopol 934 and Sodium CMC. Containing 1.55%of Cassia tora extract, Glycerin, Methyl paraben, Propyl paraben and required amount of distilled water and neutralized by drop wise addition of tri-ethanolamine to get gel like consistency. The results of physiochemical parameters of formulations were pH (6.8 to 6.89), viscosity, spreadability, extrudability, in-vitro release respectively. Concentration and combination effect of Carbopol 934 and Sodium CMC showed increased consistency and sustained action with increase in concentration.