Super disintegrants

Dispersible drug delivery methods are widely utilized nowadays to increase patient compliance and bioavailability. Dispersible tablets have drawn a lot of interest over the last three decades as a better option to traditional tablets and capsules because of their enhanced solubility, stability, and patient compliance. Dispersible tablets may be a better option, particularly for medications that are sensitive to gastrointestinal fluids, to cover up the bitter taste of the medication, and for patients who fall into the paediatric, geriatric, bedridden, postoperative, or other patient categories and may have trouble swallowing traditional tablets and capsules. These tablets instantly break down in the water to create the suspension. The key component of a dispersible tablet is the super disintegrants. When a dispersible tablet comes into touch with water, it becomes moist and swells significantly, which causes it to dissolve rapidly. The improved compliance among patients is facilitated by the new medicine administration mechanism. Among these are pills that dissolve quickly. Benefits of readily dispersed tablets include precise dosage, ease of production and transportation, strong chemical and mechanical stability, and a perfect substitute for elderly and paediatric patients. Because of its many benefits, such as simplicity of ingestion, pain avoidance, adaptability, and, most importantly, compliance from patients, the oral route of taking medication continues to be the most optimal method. The most popular solid dose forms are tablets and capsules.

The objective of this paper was to attempt to investigate a review the Development and evaluation of mouth dissolving antinflammatory tablet containing fenoprofen. MDT is used methods to improve patient’s compliance have always attracted scientists towards the development of fancy oral drug delivery systems. Among them, mouth dissolving drug delivery systems (MDDDS) have acquired an important position in the market by overcoming previously encountered administration problems and contributing to extension of patent life. In the present scientific scenario the drug delivery technology has become highly competitive and rapidly evolving with ever increasing demand. Fast dissolving tablet (FDT) is one such type of an innovative and unique drug delivery system which is swiftly gaining much attention in the research field of rapid dissolving technology. Oral route is the most expedient and safest route of drug delivery because of wide range of drugs are administered through this route. Recently researchers have developed fast dissolving tablet (FDT) which dissolve or disintegrate rapidly in mouth saliva without intake of water. This novel drug delivery such as FDT or MDT (mouth dissolving tablet) has overcome many disadvantages like dysphagia or non accessibility of water while travelling. When compared with conventional dosage form FDT can be a useful alternative as well. This review article contains different techniques used for preparing FDT, silent features, various patented technologies, and mechanism of super disintegration, challenges faced and the limitations.