Comparative study

Hypertension is the most important risk factor for cardio vascular disease. But, the key question remains: which of the many available types of blood pressure lowering drugs is the better choice as first line medication. Hence, the prospective, randomized, single blind , Comparative study was conducted  at tertiary care Hospital to  assess  the beneficial outcomes of drugs by comparative method. The study concludes that the physicians were prescribed the ACEIs for hypertension with various co morbidities as per JNC-7 guidelines. The study conclude that the A+E+N is the most effective combination therapy for better control of hypertension. The study indicates that the combination therapy can be individualized according to the presence of co morbidities  with  HTN.

Acacia seyal is well known in the Sudanese traditional medicine for its therapeutic value. The pleasantly fragrant fumigate bath, locally known as Dokhan, mainly from the stem or stem wood of the plant is widely used for cosmetic and medicinal purposes. The investigation and a composition of antioxidant and antimicrobial activities of the dry distillates (Dokhan) prepared by dry distillation method from the stem, stem wood and stem bark is the objective of the present study.  The results showed remarkable antioxidant and antimicrobial activities of the dry distillates. The antioxidant activity assayed by using DPPH radical scavenging technique was found to be 94±0.01%, 95±0.03, 93±0.02 for the stem, its wood and bark respectively compared to Propylgallate, standard antioxidant agent 90±0.01. The disc diffusion procedure was used for antimicrobial activity assessment which revealed the highest activity in the stem wood dry distillate with inhibitory zone diameter ranging from 20 to 36 mm.