polymer

A class of polymeric materials known as hydrogel products have a hydrophilic structure that allows them to store enormous amounts of water in their three-dimensional networks. More than any other form of synthetic biomaterial, they most nearly resemble genuine living tissue because of their high water content, porosity, and soft consistency. Hydrogels may also be prepared into a wide range of physical forms, such as coatings, films, microparticles, and slabs. Hydrogels are so often utilized in clinical practice and medicine for a variety of purposes, such as cellular immobilization, tissue engineering and regenerative medicine, diagnostics, separation of biomolecules or cells, and barrier materials to control biological adhesions. This biomaterial has the capacity to expand and store huge volumes of biological fluids. They are mushy when swollen.

Polymer grafting open a new window to pharmaceutical formulation. This article review about the different natural polymer and their application in pharmaceutical industry. Techniques such as grafting, crosslinking, blending and composite formation techniques are accustomed to modify the polymer. Recently, polymer grafting method received a wide attention than the other methods employed in the modification of the polymer. Polymer grafting can be achieved by covalent bonding of monomer to the polymer. In this review, techniques such as chemical grafting, radiation grafting etc. are also discussed.

  In the present research paper, anticonvulsant Sodium valproate tablets were prepared using two different disintegrating agents in different ratio. Acrycoat-L-100 polymer was used as an enteric coating material. The tablets were formulated using direct compression method. Further post formulation parameters like hardness, friability, weight variations and content uniformity were studied. The results suggested, that the prepared enteric coated tablets specifics all the criteria of the standard formulation as per specified in monographs.