pheretima posthuma.

Medicinal plants and their secondary metabolites have been used since last few centuries as remedies to treat diseases and disorders. As per WHO report (1993), 80% of world population continues to depend on medicine isolated from medicinal plants. Presently there is an increasing interest in herbal medicine related to isolation, characterization and pharmacological screening of extracts obtained from medicinal plants. The ethanolic extract of Leucas indica var. martinicensis was studied for preliminary phytochemical screening and anthelmintic activity at various concentrations (i.e., 10mg/ml, 25mg/ml, 50mg/ml, 100mg/ml) by using adult Indian earth worm, pheretima posthuma from in nalgonda region. Phytochemical Screening revealed the presence of Alkaloids, carbohydrates, and saponins. The mean paralysis time and mean death time for each sample was calculated and compared with the Albendazole which is taken as standard. The result was found that Leucas indica var. martinicensis had an anthelmintic activity which was greater than standard Albendazole.

The plant Butea monosperma is a medium sized deciduous tree Belongs to family “Fabaceae” is called as “Dhak & Palas” in Hindi. This plant is used as Anti-inflammatory agent, Healing Power and Curative Properties, Diarrhoea and Dysentery, Skin Disorders, Diabetes, Leucorrhoea, Sore Throat Retention of Urine and Used as dye. In present study methanolic extract of plant is used for its anthelimintic property. The Anthelimintic activity was evaluated on adult Indian Earth worms (pheretima posthuma). Albendazole suspension was used as standard and antheliminitc potential of plant extract was evaluavated at three different concentrations. And found that methanolic extract of plant Butea monosperma contain significant and dose dependent antheliminitc activity.