bilateral common carotid artery occlusion

The present study was designed to investigate te antioxidant activity oof methanolic extract of Morinda Tinctoria Roxb against (MEMT) fruits in the cerebral ischemia induced animal model system.  Global cerebral ischemia was induced by temporary bilateral common carotid  artery occlusion for 15 min followed by reperfusion in Sprague Dawley Rats  and the animals were pre-treated with MEMT (200 and 400 mg kg-1) for 1 week before induction. After induction of ischemia by BCCAO animals were again treated with MEMT for 1 week and the animals were sacrificed. Homogenized content of brain were estimated in control, sham and treatment groups. The MEMT showed the significance of p