Technologies

Improvement of patient’s compliance has always a challenge towards the development of oral drug delivery system. Different dosage forms are available in the market among all oral dosage form is preferred one. However, the incompliance of pediatric & geriatric patients the scientists worked towards fast dissolving solid dosage form to encounter existing drawbacks with unique palatability and rapid disintegration. The concept of fast dissolving tablet came into existence in late 1970s. Recently, fast dissolving drug delivery systems have started gaining popularity and acceptance as new drug delivery system, because they are easy to administer and lead to better patient compliance. For further improvement in existing technologies and newer technologies has been succeeded and still research is going on in improvement with its preparation methodologies all over the globe. Fast dissolution tablets have faster disintegration and dissolution rate and release within 30 seconds as they come in contact with saliva. These systems also obviate the requirement of carry water during drug administration. As fast dissolving tablets falls under desired expectation of safer, convenient and economical solid dosage forms, several techniques have been developed to improve disintegration quality in the recent past years. This article mainly focuses on patented technologies with recent advancement made so far in the field of the fast dissolving tablets.

Targeted drug delivery systems deliver the drug to the site of action. Colon Targeted drug delivery is considered as one of the most convenient pathway for the delivery of the drugs or therapeutic agents and used in the treatment of the local diseases. Microencapsulation is widely used in the pharmaceutical and other sciences to mask taste/odors, prolong release, impart stability to drug molecules, improve bioavailability, and as multiparticulate dosage forms to produce controlled or targeted drug delivery. Microencapsulation is the process in which small droplets or particles of liquid or solid material are surrounded or coated by a continuous film of polymeric materials. Microencapsulation system offers potential advantages over the conventional drug delivery systems. In this present article various technologies for the preparation of microcapsules for the purpose of colon targeted drug delivery systems are reviewed.