Phytochemical screening

The main aim of the study was to investigate phytoconstituents and anti-helminthic activity in the canthium parviflorum root. Roots were collected and shade dried. Extraction was carried out by continues hot percolation method using ethylacetate and methanol as solvents. Both the extracts were subjected to phytochemical screening, using standard methods, where as anti-helminthic activity was evaluated at three different concentrations on Pheretima Postuma; the parameters like time of paralysis and time of death were determined. The extract showed significant activity in the dose dependent manner and methanolic root extract showed significant activity than that of standard drug Albendazole. This might due to the presence of secondary metabolite tannins which are responsible for the activity.

Gastric ulcer is one of the most prevalent gastrointestinal disorders, which affects approximately 5-10% of people during their life. In recent years, abundant work has been carried out on herbal medicine to clarify their potential efficacy in gastric ulcer prevention or management. Here, present study was carried out to investigate antiulcer activity of ethanol extract of Houttuynia cordata Thumb. (Family: Saururaceae) leaves in aspirin plus pylorus ligated ulceration in the albino rats. Preliminary ethanol extract of H. cordata was subjected to the phytochemical study. Two dose levels i.e. 250 and 500 mg/kg were selected for the further study. In Aspirin plus pylorus ligation induced ulcer model, various parameters were studied viz. gastric volume, pH, total acidity, free acidity, and ulcer index. Ranitidine at 50 mg/kg was used as the standard drug. Pretreatment of ethanol extract of H. cordata leaves showed significant (P

This study was performed to evaluate the In vitro antimicrobial activity of entire parts of aqueous and methanolic extracts of Sphaeranthus amaranthoides Burm. The antimicrobial activities of medicinal plant extracts used for the treatment of parasitic diseases were examined with four bacteria – two from Gram positive group (Bacillus subtilis and Staphylococcus aureus) and rest two from Gram-negative group (Escherichia coli and Salmonella typhi) following disc diffusion method. The methanolic extract revealed antibacterial activity more than the aqueous extract. Both the extracts showed less activity against Bacillus subtilis and where as Salmonella typhi no inhibition (NI). It showed more activity on Escherichia coli compared to standard. Both the extracts showed minimum inhibitory concentration (MIC) of 25mg/ml on Bacillus subtilis and 12.5mg/ml on Staphylococcus aureus. Totally the methanolic and aqueous extracts of Sphaeranthus amaranthoids showed good anti bacterial activity. Phytochemical screening revealed the presence of steroids, alkaloids, sugars, phenolics, flavonoids, saponins, tannins and amino acids with mottled degree

The present article is designed for screening and evaluation of biomolecules, antimicrobial potential from extracts of A. nallamalayana (root), belongs to the family Acanthaceae. A. nallamalayana is the rare and endemic to the forests of Nallamalais, the nucleus of Eastern Ghats, India. It has been used in the folklore system of medicine for the treatment of mouth ulcers, leucorrhoea and abortion / sterility. Phytochemical screening and antimicrobial activity of the test species is hither to not reported. The phytochemical investigation on all such extracts revealed the presence of flavonoids, alkaloids, phenols, steroids and triterpenoids. The antimicrobial activity of various extracts (petroleum ether, ethyl acetate and methanol) of A. nallamalayana revealed that the methanolic extract (root) exhibited maximum inhibition on all test pathogens followed by ethyl acetate while petroleum ether failed to show inhibition. Klebsiella pneumoniae, Salmonella typhimurium, Staphylococcus aureus were proved as most sensitive while Bacillus subtilis as resistant strain to the test extracts.

The present paper focus on the phytochemical screening and antimicrobial activity of Phyllanthus narayanaswamii (Euphorbiaceae), a critically endangered and endemic species to the East Godavari & Visakhapatnam hills of North Eastern Ghats. In the present study the alcoholic extracts of leaves, shoot and root of P. narayanaswamii were studied for their antibacterial activity by agar disc diffusion method against both Gram positive, Gram negative and one fungal strain. It was observed that, alcoholic extracts of leaf showed the highest antimicrobial activity against the pathogenic microorganisms followed by shoot and root extracts. The minimum inhibition and minimum bacterial concentrations (MIC and MBC) were determined by microdilution method using 96-well microtiter plate method. As the disc dosage level increases the inhibitory effect also increased.