Pharmacological activities.

Herbal medicinal plants are the gift of nature to the human beings. The present review is an effort to give a detail literature survey and discovering the hidden Marvels of Commiphora wightii also its remarkable health benefits in human beings. Worldwide Commiphora wightii is also known as Guggul is known for its anti-inflammatory property. Along with these it has many pharmacological activities like in the treatment of Rhematoid arthritis, fibrinolysis, weight management, Cardioprotective action, thyroid function regulation, antioxidant support and in metastatis Inhibition. It contains various chemical constituents like guggulsterones, guggulipid, commiphoric acid, Monoterpenoids, guggultetrols, Steroids, flavonoids, diterpenoids, sesquiterpenoids, triterpenes, lignans and various amino acids which contribute to various therapeutic property.

Benzimidazole is the heterocyclic compound which contains a phenyl ring fused to an imidazole ring, Benzimidazole analogs are of crucial importance because of their different clinical applications and biological activity. Benzimidazoles are known as an optimistic class of bioactive heterocyclic compounds possessing a wide variety of biological activities. Benzimidazole derivatives play an important role in medical field with so many pharmacological activities such as antimicrobial, antiviral, anticancer activity, antioxidant, antiparasitic, antiproliferative, antitumor, anti-HIV, anticonvulsant, antiprotozoal, analgesic and anti-inflammatory, antihypertensive, anticancer, androgen receptor antagonist, vasorelaxant etc. This review is summarized to understand the chemistry of various derivatives of substituted benzimidazoles with their pharmacological activities.

The plant Sida spinosa Linn belongs to the family Malvaceae, which is a popular Ayurvedic remedy for the treatment of various disorders mainly in the treatment of healing of wounds. Sida spinosa Linn., is one of the important species of this genus which is found through out the tropical and subtropical region of both hemispheres of India and Srilanka. It is also known as “Nagabaala” in Hindi and Sanskrit. The plant name Bala is coined on the name of ‘Parvati’ (Goddess of strength and beauty).It is abundantly found throughout the hotter parts of India from North West India to Ceylon and Tropical and subtropical regions of both hemispheres. The root, bark, leaves of this plant are traditionally used for the treatment of leucorrhoea, respiratory disorders, healing of wounds, tonic, diaphoretic, asthma, chest ailments and also in diarrhoea and dysentery. The plant was found to contain phytoconstituents like alkaloids, glycosides, phytosterols, tannins, flavanoids, lignins and saponins. The plant is rich in alkaloids and various phytochemical constituents like glyceryl-1-eicosanoate and 20-hydroxy, 24-hydroxymethylecdysone, Apigenin and Kaempferol has been isolated from this plant. This plant showed antipyretic & antimicrobial, anti diabetic, antioxidant and diuretic activity. This review summarizes the list of phytochemical compounds isolated and pharmacological activities over the past few decades.