N-(7-substitutedthiocarbamidoquinoline-4-yl)-N
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Publications Tagged with "N-(7-substitutedthiocarbamidoquinoline-4-yl)-N"
1 publication found
2014
1 publicationEco-Friendly Synthesis and Antimicrobial Activity of N-[7-(5-Substitutedimino-3-Amino)-1,2,4-Dithiazo-4-Yl]-N,N-Diethyl-Pentane-1,4-Diamine
Heteroacyclic and Heterocyclic containing drugs showed remarkable and noticeable drug absorption, transmission and drug effects; hence they created their own identity and importance in pharmaceutical, medicinal, agricultural and drug sciences. Benzonido and pyridino, dithiazolo, quinolino and alkylamino heterocycles showed important applications in industrial, pharmaceutical, medicinal and drug chemistry. Considering all these facts into consideration recently in this laboratory interaction of N-(7-chloroquinoline-4-yl)-N,N-diethyl-pentane-1,4-diamine (1) was carried out with thiourea (2) in ethanol medium to isolate N-(7-thiocarbamidoquinoline-4-yl)-N,N-diethyl-pentane-1,4-diamines (3). N-(7-thiocarbamido quinoline-4-yl)-N,N-diethyl-pentane-1,4-diamines on further interactions with various isothiocynates (4) in acetone-ethanol medium produces N-[7-(1- substituted) -2,4-dithiobiureto)-4-yl]-N,N-diethyl-pentane-1,4-diamine (5) which were successfully oxidatively cyclised into N-[7-(5-substitutedimino-3-amino)-1,2,4-dithiazo-4-yl]-N,N-diethyl-pentane-1,4-diamine (6) these reactions are hither to unknown. The justification and identification of the structure of these newly synthesized compounds had been established on the basis of chemical characterization, elemental analysis and through spectral data.
