Metal complexes

The Complexes of Mn (II) and Cr (II) with amino acid cysteine were synthesized and Characterized by elemental analysis, SEM, TGA. In these complexes the amino acid coordinated to 1:2 with metal and they exhibits octahedral geometry. The catalytic activity of these complexes was studied in olefins using eco-friendly nontoxic molecular oxygen as oxidant.

A new azo dye Schiff base ligand, namely N, N′-bis (5-(4-nitrophenyl) diazenyl)-2-hydroxybenzylideneamino)ethylenediimine (NDHBDED) has been synthesized and characterized by analytical techniques. And transition metal complexes of Mn (II), Co (II), Cu (II) and Ni (II) were synthesized by the derived azo dye Schiff base. The complexes were characterized for the elemental analysis, molecular weight determination, electronic spectra, spectral analysis, pH metric method, conductance measurement, magnetic moment measurement at room temperature. Analytical data reveal that Mn (II), Co (II), Cu (II) and Ni (II) complexes posses 1:1 metal-ligand ratios. Schiff base and synthesized complexes were screened for antibacterial and antifungal activities. Co (II) and Cu (II) complexes have been found to be more effective for antimicrobial activity.

A pestle and mortar-assisted solvent-free condensation of salicylaldehyde and 2-aminopyridine efficiently afforded a NO donor Schiff base ligand in high yield. This is an environmentally benign method, as satisfactory results were obtained in solvent free conditions with excellent yields, short reaction time, and operational simplicity in the experimental procedure. Copper(II) complex of this ligand were synthesized. Schiff base ligand and its complex were characterized by their melting point, elemental analysis, IR and 1H NMR spectra. In addition, DNA-binding properties of the metal complex were investigated using absorption spectroscopy, viscosity measurements and thermal denaturation methods. The DNA photoclevage experiment shows that, the complex act as effective DNA cleavage agent.

A new series transition metal complexes of Cu(II), Co(II), Ni(II) and Zn(II)  complexes have been synthesized from 2-(4-amino-5-mercapto-4H-1,2,4-triazol-3-yl)phenol (AMPT). The nature of bonding and the geometry of the complexes have been deduced from elemental analyses, magnetic susceptibility, infrared, electronic, 1H NMR, 13C NMR, and EPR spectral studies. The redox behavior of copper complexes was studied by cyclic voltammetry.  The second harmonic generation (SHG) efficiency was measured by Kurtz and Perry method. The ligand and their metal complexes were screened by Well diffusion method. The interaction of complexes with CT- DNA was investigated by viscosity measurement. Results suggest that all the complexes bind to DNA via an intercalative mode. The DNA cleavage ability of all the complexes was examined on calf thymus (CT-DNA) plasmids using gel electrophoresis experiment in presence of H2O2. From the results it is concluded that all the complexes cleave DNA.