Lakshmi B

The present work deals with the use of folklore medicine by tribal and non-tribal communities of Nalgonda district, Telangana state, India for controlling diabetes, a chronic disease. Here it is focused on the use of plant species as folklore medicine to cure diabetes by the ethnic groups. Preliminary phytochemical analysis was carried out with different extracts like distill water, petroleum ether, chloroform and methanol of folk medicine samples and their constituent plant parts from Nalgonda district. The folk medicine and the individual plant parts present in the sample showed the presence of similar kind of phytochemicals with various screening tests for the control of diabetes.

  Gymnosporia montana belonging to the family Celastraceae commonly known as Vikalo.  It is a shrub or tree growing wild in dry areas and is commonly found in Gujarat. It is widely used in treating sore, ulcer, gastro-intestinal disorders, toothache, and dysentery. The dried powder of leaf of Gymnosporia montana was subjected to the phytochemical screening for the presence of various phytoconstituents like alkaloids, flavonoids, saponins, tannins, anthraquinones, and carbohydrates, etc. Effectiveness of methanolic extracts of leaf of Gymnosporia montana was evaluated (100, 200 and 300 mg/kg; p.o.) against carrageenan-induced rat paw edema, and cotton pellet-induced chronic inflammation. Further, methanolic fraction of the plant was also evaluated (200 mg/kg; p.o.) in tail flick model using rats as well as acetic acid-induced writhing response using mice. Pretreatment with methanolic fraction showed significant (p