L.J.Paliwal

Microwave assisted solvent free synthesis of cyclohexenone and indazole derivatives were carried out by chalcones derived from different acetophenones and 1-naphthaldehyde. Structures of the compounds have been characterized by IR, 1H NMR, Mass spectrometry and elemental analysis. All the synthesized indazole derivatives were screened for antibacterial activity and are found to posses moderate to good activity against some species of bacteria.

Phenylene-1, 4-oxy-bis-hydantoins have been synthesized from 5-bromohydantoin and substituted quinol (1,4-dihydroxybenzene) in the presence of K2CO3 in dioxane. The structures of newly synthesized compounds have been established on the basis of IR, NMR and Mass spectral data. These compounds were screened for their antibacterial activity against gram +ve and gram – ve bacteria. This phenylene-1, 4-oxy-bis-hydantoins are so far not reported in literature.