Harisha CR

Hypothyroidism is emerging as one of the global health issues. The analysis of the symptomatology of Hypothyroidism in the light of Ayurvedic principles reveals that the pathogenesis and manifestations of hypothyroidism occurs due to dysfunction of Agni. The trial drug Triphladya Guggulu, cited in Yogaratnakara for the management of Gandamala, contains Deepana, Pachana, Anulomana and Vatakapha shamaka drugs, targeting the Agni which is the main seat of pathogenesis. Pharmacognostical & Analytical study of Triphaldya Guggulu has been carried out for the evaluation of its efficacy in Hypothyrodism. On pharmacognostical study, Starch grains & fibres of Shunthi, Black debris of Maricha, Epidermal cells with Oil Globules & stone cells of Pippali, Sclerides of Haritaki & Vibhitaki, Trichoma of Vibhitaki, Tannin content of Haritaki, Fibres & silica deposition of Amalaki, Prismatic crystals & stone cells of Kanchnara were identified. Analytical study showed 10 spots at 254 nm and 11 spots at 366 nm.

Ayurveda, being as ancient system of medicine, which comprises hundreds of Kalpanas of pharmaceutical preparations but only few of these Kalpanas are in practice. In this modern era many good preparations have been extinguished in the passage of time among these, Varti Kalpana is main one. Now-a-days, when human life is very fast, we should be ready to make necessary changes in our science according to the need of hour. In present study Nimbadi Yonivarti is selected for the management of Swetapradara which has been mentioned as Anubhuta Yoga by Vd. Devisharan Garga Ayurveda Upadhyaya in “Nari Roganak. The present study was aimed at setting up a standard profile of Nimbadi Yonivarti which was prepared using pharmacognostically authenticated raw drugs followed by subjecting it to detailed pharmacognostical, physicochemical and phytochemical (including Thin Layer Chromatography) analysis as per standard protocol. The observations were systematically recorded. Pharmacognostical findings (crystals, epicarp cells, trichom, etc.) confirm the ingredients present in the finished product. Identified phytochemical components (Carbohydrates, tannins, fanolic compound, glycosides, steroids, flavonoids.etc.) support the intended action of the formulation in vaginal discharge.