Dimkpa Uchechukwu

Diabetic mellitus goes with metabolic disorders involving hyperglycaemia and lipid disorders. The study investigated the activity of aqueous ginger extract on the glucose level and lipid profile of cholesterol-fed diabetic rats.  The rats were randomly distributed into four groups of 5 rats per group. Group A (control) were placed on normal rat feed. Diabetes was induced in groups B, C, and D by intraperitoneal administration of one dose of alloxan monohydrate (150mg/kg/bwt) and fed diet mixed with 1% cholesterol. The rats in groups C and D were orally administered with 250 and 500mg/kg/bwt of ginger extract respectively for 14 days. Biochemical parameters were analysed by standard methods. A significant decrease (P0.05). There was a statistical increase in the serum triacylglycerol level in group B compared to group A (P