surgical prophylaxis.

Surgery is the art of practice or work of treating diseases, injuries or deformities by manual or operative procedures. Before the start of operative procedures, a very brief course of antibiotics is initiated. This study aims to study the antibiotic utilization in surgical prophylaxis. This was a prospective and observational study conducted on 303 patients for a period of 06 months with the approval of institutional ethical committee from the Apollo multi specialty hospital & research center. Those who satisfied the study criteria were consented and participated for the study. Among 303 patients 183 male and 120 females were enrolled for the study. Most of the participants were in the age group of 31- 40 years. 205 patients had a clean- contaminated wound. Inj. Cefuroxime was the most prescribed prophylactic and post-surgical antibiotic in this study to avoid surgical site infection. None of the patients had developed any surgical site infections and the results which were satisfiable. Rational therapy with antibiotics helped patients to improve the quality of life by reducing financial and physical burden.