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American Journal of PharmTech Research

Keyword

spectrometry

Explore 1 research publication tagged with this keyword

1Publications
4Authors
1Years

Publications Tagged with "spectrometry"

1 publication found

2020

1 publication

Study of the Analgesic and Toxic Effects in Vivo of a Selective Ethyl Acetate Extract of the Leaves of Gossypium Barbadense L. (Malvaceae) and Structural Characterization of an Isolated Phytoconstituent

Koffi Atta Kouao Olivier et al.
6/1/2020

Gossypium barbadense L. is a medicinal Malvaceae used as an indispensable intrant in the endogenous medication of skin super infection caused by shingles in Côte d'Ivoire. The objective of this study was to study the analgesic and toxic effects in vivo of the extract with ethyl acetate GB2.3, obtained from the hydroalcoholic crude extract of the leaves of Gossypium barbadense L., and to characterize a phytocomponent of the extract. The results obtained showed that the extract showed a significant analgesic effect by inhibition at 73.66% of the pain induced by acetic acid in mice and that it had insignificant toxicity at the dose of 100 mg/kg body weight. A phytocompound was isolated with a yield of 15.21% by HPLC, whose molecular structure was determined by spectrometry (MS, IR, NMR 1H, 13C).

Keyword Statistics
Total Publications:1
Years Active:1
Latest Publication:2020
Contributing Authors:4
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