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American Journal of PharmTech Research

Keyword

cytotoxic.

Explore 1 research publication tagged with this keyword

1Publications
5Authors
1Years

Publications Tagged with "cytotoxic."

1 publication found

2016

1 publication

Synthesis and Evaluation of New Isatin Derivatives for Cytotoxic and Antioxidant Activities

B.Vineela et al.
2/1/2016

In the present study N-(2-oxosubstitutedindolin-3-ylidine)-2-phenylacetohydrazides (IV a-h) have been synthesized in good yields and characterized by IR, PMR and mass spectral analyses. Compounds were evaluated for their preliminary in vitro cytotoxic activity against HeLa cancer cell lines by standard MTT assay and also were screened for antioxidant activity by DPPH method. Our results shown that two of the analogues IVf and IVc  are potent antioxidant agents and IVb and IVg are potent cytotoxic agents.

Keyword Statistics
Total Publications:1
Years Active:1
Latest Publication:2016
Contributing Authors:5
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