benzothiazole

Preparation of new series of acridin-9-yl-bis-benzothiazol-2-yl-amines have been developed by intra-molecular cyclization of 1-acridin-9-yl-1-benzothiazol-2-yl-3-aryl thiourea with bromine in acetic acid and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis by BACTEC radiometric method. Constitutions of compounds were confirmed by FTIR, 1H-NMR, 13C-NMR spectral methods. Simple work-up procedure and excellent yield of the products are the merits of the route.