Sensitivity

A study was on the physical concepts ( transmission of sound waves among different parts of the body for medical diagnosis purposes )  , methods of detection two dimensional 2D commonly used  , modern methods as color Doppler ( Duplex ) , in addition new techniques that have developed and used together with the device ,  such as ( contrast medium , catheters using techniques , guidance technique for therapeutic injections and  a sample taking purposes  (Biopsies) . The research included a study of a 50 clinical cases of different parts of the body, ages, gender over two months. After cases discussion showed that the device is useful as initial step and very sensitive tool in the medical clinical field, specifically if the new techniques are applied, in turn increase the benefits of the device, get good clinical results and finally minimize the ionizing radiation exposure of the other devices.

The present review provides an overview on recent development and capabilities of inductively coupled plasma mass spectrometry (ICP-MS) technique which allows the determination of elements and isotopes from the biological tissues and related materials with the spatial resolution which typically ranges from 10 to 100 μm. The outstanding properties such as high sensitivity (ranging, ppt–ppq), relative salt tolerance, compound-independent element response and highest quantitation accuracy leads to an unchallenged performance of ICP MS in its efficiency in detection, identification and quantification of trace elements. The elements that are detected are mostly ‘‘trace’’ and can be analyzed from both body tissues and body fluids. The accurate determination of elemental distribution in neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease, etc., helps in the better understanding of the particular diseases. ICP-MS can be applied also in environmental and bioanalytical fields when coupled/combined with different separation techniques for the quantitative determinations.