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American Journal of PharmTech Research

Keyword

Magic bullet

Explore 2 research publications tagged with this keyword

2Publications
6Authors
2Years

Publications Tagged with "Magic bullet"

2 publications found

2020

1 publication

A Review on Long-circulatory Liposome and Magic Bullet Concept

Pravin Ashok Nikam et al.
6/1/2020

The long circulatory liposome means shows action towards target organ longer period of time. Liposome are the concentric bilayer in which aqueous volume entirely envelope by the lipid bilayer used to transfer enzymes, protein and drugs to targets cancer cell or tissue. These are chemical moieties in which action towards target organ. It was first discovered by 1965 and soon was proposed drug delivery system. There are numerous application like anti fungal, anti cancer, anti inflammatory and anesthetic drugs. The magic bullet concept of Poul-Ehrlich et al; through very late, offers a logical solution to the age old problem unrelated and unwanted effect of therapeutic agent and optimizing the drug therapy in its true sense. The controlled, sustained and controlled drug delivery can be considered as the magic bullet concept. The long circulatory liposome gives the stealth effect called as killer bomber to cancer cell and arrest the Mitosis of M-phase and G-phase.

2017

1 publication

A Review on Liposome: The Cancer Targeting Aspects and Effective Upgraded Vesicular Systems

Santosh Dattu Navale et al.
4/1/2017

Liposome are the concentric bilayer means core of center in which aqueous volume entirely envelope by the phospholipids bilayer used to transfer enzymes, protein and drugs to targets cancer cell or tissue. These are chemical moieties in which action towards target organ. It was first discovered by 1965 and soon was proposed drug delivery system. There are numerous application like anti fungal, anti cancer, anti inflammatory and anesthetic drugs. The magic bullet concept of Paul Ehrlich through very late, offers a logical solution to the age old problem unrelated and unwanted effect of therapeutic agent and optimizing the drug therapy in its true sense. Drugs would be targeted by virtue of groups having affinity for specific cells, tissues or organs. Liposome having also its modifications or upgraded versions likes enzymosomes, hemosomes, virosomes, and erythrosomes. Liposome has emerged as a dynamic mode for targeted drug delivery. Ligands confer specificity on a non specific reagent. Although controlled and sustained drug delivery can be considered as the magic bullet concept. We can look forward to many more clinical products in the future.

Keyword Statistics
Total Publications:2
Years Active:2
Latest Publication:2020
Contributing Authors:6
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