Immunology

The concept of "body defenders" encompasses a wide range of biological and technological systems designed to safeguard the human body from various threats. This review explores both the body's natural defense mechanisms such as the immune system, skin barrier, and reflex responses and cutting-edge external protective technologies, including body armor, exoskeletons, and smart protective wearables. The body's innate and adaptive immune responses play a crucial role in defending against infections, toxins, and other biological hazards. Additionally, advancements in engineered protective gear, particularly in military, law enforcement, and occupational safety, have significantly enhanced human resilience against physical harm. Innovations such as exoskeletons for mobility support and injury prevention, as well as intelligent textiles embedded with sensors to detect environmental hazards, are reshaping the landscape of body defense. This review also examines the ethical considerations, challenges, and future prospects of body defense technologies, addressing issues related to privacy, accessibility, and sustainability. By integrating insights from multiple disciplines, this study provides a holistic perspective on the evolution of body protection systems, paving the way for future advancements that enhance human safety and well-being in an increasingly unpredictable world.

The present study is designed to review whether the combination therapy of Infliximab and Methotrexate is better than Methotrexate monotherapy. We have reviewed that combination therapy of TNF-  inhibitors and Methotrexate in RA. How TNF-alpha inhibitors (Infliximab) and Methotrexate performed in randomized controlled trials when compared to Methotrexate in Methotrexate naive Rheumatoid Arthritis patients.