Curcuma caesia

This study aimed to evaluate the phytochemical profile and antimicrobial potential of extracts derived from Curcuma caesia rhizomes and Nardostachys jatamansi roots. A total of 250 g of Curcuma caesia and 80 g of Nardostachys jatamansi were subjected to solvent extraction. The yields of Curcuma caesia extracts were 2.22% in petroleum ether and 7.15% in ethanol. Phytochemical screening of the ethanolic extracts confirmed the presence of several bioactive constituents, including alkaloids, flavonoids, terpenoids, tannins, phenolics, saponins, glycosides, and proteins. The total phenolic content was measured at 171 mg/g for Curcuma caesia and 393 mg/g for Nardostachys jatamansi, expressed in gallic acid equivalents. Similarly, the total flavonoid content was 175 mg/g and 410 mg/g, respectively, in terms of rutin equivalents. A polyherbal gel was formulated using these extracts, with the G3 combination formulation showing superior performance in antimicrobial activity tests, as evidenced by a larger zone of inhibition. Furthermore, dermal safety assessment revealed no skin irritation, indicating its suitability for topical application. Overall, the findings support the potential of this herbal gel as a safe and effective natural antimicrobial agent.

The objective of this study was to produce the rhizome of Curcuma caesia's ultraviolet-visible (UV-VIS) and Fourier transform infrared (FTIR) spectrum profiles. For the proximate analysis, the extracts were examined in both visible and ultraviolet light. The C. caesia crude extracts. Using a Perkin Elmer spectrophotometer, the rhizome was scanned at wavelengths between 200 and 800 nm, revealing the characteristic peaks. A Perkin Elmer spectrophotometer system was used for the FTIR method, which was used to identify the characteristic peak values and their functional groups. The C. caesia UV-VIS profile. The rhizome methanolic extract had absorption values of 0.617, 1.235, and 0.557, respectively, at peaks at 256.00 nm, 288.00 nm, and 330.00 nm. The FTIR range was utilized to distinguish the useful gathering of the bioactive parts in light of various pinnacle values in the locale of infrared radiation. The current study's findings confirm the presence of the pyrocatachol derivative.