Antibiotic Resistance

To evaluate the general public's awareness, knowledge, attitude, and behavior about the use of antibiotics and the emergence of antibiotic resistance. From January to April 2025, A study using a cross-sectional survey standardized question was given to the participants.  To gather information from 205 respondents, a questionnaire was created. In order to gather information on sociodemographic traits, antibiotic use, antibiotic knowledge, and antibiotic resistance, the survey was divided into three components. A total 205 participated in this study, 52.7% were male and 46.3% were female successfully answered every question, demonstrating a 99% response rate.  118 participants, or 57.6% of the sample, agreed with that the use of antibiotics was a significant and grave public health concern in your community. And the 39 (19%) patient ware not aware about antibiotic resistance is a growing concern in your community. The result of study show that patient and public aware to use of antibiotic and antibiotic resistance. The present study discovered that a high proportion of participants unaware being of "Antibiotic resistance and its risk to public health". To change their attitudes about the use of antibiotics and their knowledge and views of antibiotic resistance, more educational programs are required.  Overall, the study participants had an extensive knowledge of antibiotic resistance.

Antimicrobial prophylaxis in cardiac surgery has been demonstrated to lower the incidence of postoperative infection. Inappropriate antimicrobial prophylaxis, as inappropriate selection of the antimicrobial agent or dosing regimen, can increase the prevalence of antibiotic resistant strains, prolong hospital stay, cause postoperative infection, and negatively affect an institution’s pharmacy budget for antibiotics. To assess the current postoperative prophylactic antibiotic protocols applied in the cardiac surgeries department in Ain Shams University teaching hospitals with respect to others and to international guidelines for antimicrobial prophylaxis practice in cardiac surgery. Total of 320 paediatric and adult patients who were admitted for cardiac surgery to Ain Shams University teaching hospitals from September 2012 till March 2013.The antimicrobial prophylaxis indication, choice, duration, dose, dosing interval, and timing appropriateness were assessed against 3 international guidelines using a pre-tested, structured clinical data collection form. All patients were monitored daily during their inpatient stay until discharge. Data regarding surgery duration, mechanical ventilation duration, intensive care unit stay, postoperative stay and total hospital stay were obtained. Adherence to all antimicrobial prophylaxis guidelines was not achieved for any study patients. A statistical significant difference for the mechanical ventilation duration, intensive care unit stay, postoperative stay and total hospital stay were found concerning both the paediatrics and the adults between the infected and non-infected group. Study findings indicate that adherence to international guidelines for antimicrobial prophylaxis is far from optimal in cardiothoracic department at Ain Shams University teaching hospitals, leading to the inappropriate administration of many antibiotics.