Vinod Kumar K

The intention of this paper was to review and discuss the some of the quantitative analytical methods used in forensic science for the analysis of trace evidences collected from the various scene incidents. The forensic scientists were depend upon the instrumental analysis of trace amounts of materials like drugs, toxicological specimens, fibers, glass, GSR, soil, etc. Differences in manufacture of chemical composition are observed and that allows considerable discrimination even with very small traces of fragments. Most on GSR, GSR analysis sometimes becomes very important to right direction of inquiry, from where the GSR is obtained and from which surfaces the GSR has produced, played an important aspect of investigations. Reviews on these techniques, which are used more extensively in forensic sciences, were reported through this paper. Based on the analytical problem facing forensic scientists, our study will summarize and use these techniques to tackle them such as chromatography, Raman spectroscopy, Atomic Absorption Spectroscopy, Inductively Coupled Plasma (ICP) techniques.

  Fast dissolving, fast melting, chewable and orally dissolving or disintegrating tablets are solid dosage forms that disintegrate rapidly and dissolve in the mouth withoutwater. The principle challenge with orally disintegrating tablets (ODTs) is to develop tablet formulations for standard direct compression processes that deliver rapid disintegration, pleasant mouth feel and high breaking force for tablet robustness. Superdisintegrant affect a range of formulation parameters, including the rate of disintegration, tablet breaking force, and mouth feel. The emphasis on the availability of drug highlights the importance of the relatively rapid disintegration of a tablet as a criterion for ensuring uninhibited drug dissolution behavior. Number of factors affects the disintegration behavior of tablets. The development of fast dissolving or disintegrating tablets provides an opportunity to take an account of tablet disintegrants. Superdisintegrants are generally used at a low level in the solid dosage form, typically 1 – 10 % by weight relative to the total weight of the dosage unit. Key words: Tablet Disintegrants, Superdisintegrants, Kyron T-314.