Vedigounder Murugan
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Publications by Vedigounder Murugan
1 publication found • Active 2020-2020
2020
1 publicationSynthesis of 2-(Bis(2-chloroethyl)amino)-N-(4-((3-oxobenzofuran-2(3H)-ylidene)methyl)phenyl)acetamide Derivatives on Basis of Benzaldehydes and Acetophenones As Possible Alkylating Anticancer Agents
with Agasa Ramu Mahesh
6/1/2020
A series of 2-(Bis(2-chloroethyl)amino)-N-(4-((3-oxobenzofuran-2(3H)-ylidene)methyl) phenyl)acetamide derivatives were synthesized by fusing aurones with nitrogen mustards. Aurones being synthesized by treating 4-nitrobenzaldehydes with various derivatives of 1-(2-hydroxyphenyl)ethenone. The characterization of the synthesized compounds was done by FTIR, 1H NMR and LCMS spectral studies. The titled compounds were tested for their possible anticancer activities by in vitro methods by SRB Assay. These compounds were found to exhibit a moderate anticancer activity.
Author Statistics
Total Publications:1
Years Active:1
First Publication:2020
Latest Publication:2020
Collaborators:1
Citations:5
Collaborators