Satyanarayana D

The current study deals with the investigation of diuretic and hepato protective activity of aqueous alcoholic extract of Acacia Sinuata bark and pods. The method and procedure for diuretic activity is followed by Lipschitz et al. and the method for hepato protective activity is followed by syed mansoor ahamed et al. The present indicates regarding the chemical constituents present in the Acacia Sinuata pods and the bark extract. The preliminary phyto-chemical investigation showed the presence of alkaloids, flavonoids, terpenoids, saponins, glycosides, tannins and phenolic compounds in an aqueous alcoholic extract. The result obtained from the diuretic activity indicates the increased urine output and the increased quantities of sodium, potassium and calcium levels in collected urine. The result obtained from the hepato-protective activity indicates that the dose of 500mg/kg possessed significant hepatoprotective activity. It shows that saponins, glycosides, present in this extract may be possibly responsible for the pharmacological action.

The anthelmintic activity of fruit extracts of an Indian Medicinal plant Syzygium cuminii Linn. was evaluated on earthworms of Pheretima posthuma. This is because earthworms have anatomical and physiological resemblance with that of intestinal roundworm parasites of human beings. Here anthelmintic activity of the herb was determined by time taken for paralysis and death of earthworms after suitable treatment and comparison with standard drug piperazine citrate. The ethanol extract of Syzygium cuminii fruit at concentration of 50 mg/ml showed most pronounced activity. The results suggest that fruits of Syzygium cuminii possess anthelmintic activity. There is scope for future study on this plant.