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American Journal of PharmTech Research

Nnadi

Author Profile
Department of Biomedical Technology, School of Science Laboratory Technology, University of Port Harcourt, Port Harcourt.
3
Publications
2
Years Active
7
Collaborators
126
Citations

Publications by Nnadi

3 publications found • Active 2015-2016

2016

1 publication

Assessment of Electrolyte Levels in Hypertensive Patients in University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria.

with Henrrietta Ogadimma, Awi-Waadu, Grace Dornu-Bari, Ama-Tariah Fortune
2/1/2016

This study was designed to assess the blood electrolytes (Sodium, potassium, chloride, calcium and phosphate) levels in some hypertensive patients and healthy volunteers and to compare between them. The study aimed to determine possible changes in electrolyte levels of hypertensive patients in University of Port Harcourt Teaching Hospital. The study population was a randomly selected total of 120 healthy staff and student adults between 18-50 years of the University community and 120 patients of the University teaching hospital. 5mls of blood sample were collected separately from ante cubital vein of each of the study subjects. The serum electrolytes determined were sodium, potassium and chloride (Ion Selective Electrode method); calcium (Randox method) and phosphorus (Phosphomolybdate method).  Measurements of results were analyzed using statistical package for social science (SPSS) version 17.0. The mean values of potassium and chloride in hypertensive female patients were lower compared to those of control, while sodium and calcium showed no significant difference. The male category showed significant lower values in sodium, chloride and calcium while Phosphorous were higher in the hypertensive patients in both categories when compared to the healthy volunteers (control). The results obtained showed a significant difference at p < 0.05 significant level between hypertensive and healthy individuals for various blood electrolytes in both female male categories. We can then conclude that hypertensive patients and healthy individuals blood electrolytes is significantly different.

2015

2 publications

Changes in Electrolyte Levels in Malaria Patients in University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria

with Nnadi Henrrietta Ogadimma1* Uwakwe Augustine A2 Maria Okwudili Okata
8/1/2015

The present study was designed to assess the blood electrolytes (Sodium, potassium, chloride, calcium and phosphate) values in healthy volunteers and some malaria patients of males and females categories and to compare between them. The study aimed to examine possible changes in electrolyte levels of healthy volunteers and malaria patients in University of Port Harcourt Teaching Hospital. The subjects were 120 healthy staff and student adults between 18-50 years of the University community and 120 patients of the University teaching hospital randomly selected. 5mls of blood sample were collected separately from ante cubital vein of each of the study subjects. The serum electrolytes determined were sodium, potassium and chloride (Ion Selective Electrode method); calcium (Randox method) and phosphorus (Phosphomolybdate method).  Measurements of results were analyzed using statistical data analysis. The mean values of Sodium, potassium, chloride and calcium in healthy volunteers were higher compared to those of malaria patients. Phosphorous were higher in the malaria patients compared to the healthy volunteers. The results obtained showed a significant difference at p < 0.05 significant level between healthy and malaria individuals for various blood electrolytes. We can thus conclude that healthy volunteers and malaria patient blood electrolytes is significantly different.

Comparison of Erythrocyte Parameters Between Urban and Rural Junior Secondary School Students in Port Harcourt, Rivers and Ekwulobia, Anambra, State, Nigeria

with Nnadi Henrrietta Ogadimma*1 Dapper Datonye Victor, IDU MatthewAnenechukwu
6/1/2015

Published reports of comparison of erythrocyte parameters for newly enrolled urban and rural junior secondary school students in different geographical zone in Nigeria are relatively scanty. To determine and compare erythrocyte parameters of newly enrolled urban and rural junior secondary school students in south-south and south-east, Nigeria. The study population was a total of 240 subjects (60 male and 60 female subjects for each urban and rural area) of JSS1 students. 5mls of blood sample were collected from ante cubital vein with minimum stasis and the values of Red blood cell count, Haemoglobin, Mean cell volume, Mean cell haemoglobin, Mean cell haemoglobin concentration, Red cell distribution coefficient volume, Red cell distribution standard deviation and Haematocrit, was determined by MAXCOM MC- 6200 fully automated haematology analyzer, while the data were analyzed using Z-test; p value less than 0.05 were considered statistically significant. There were significant gender variations in the values of these parameters in both urban and rural newly enrolled students. The mean values of Haemoglobin, Mean cell volume, Mean cell haemoglobin, Red cell distribution width standard deviation and Haematocrit were significantly higher in rural males and females compared to urban males and females (p˂0.05). No significant differences were found in mean values of red blood cell count and Coefficient variation of red cell distribution width when compared both rural and urban males and females. From the above study, there is variation in the gender, age and some erythrocyte parameters amongst newly enrolled urban and rural junior secondary school students under investigation.

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