NC Obitte
Author Profile
Department of Public Health, Federal University of Technology, Owerri, Nigeria.
1
Publications
1
Years Active
4
Collaborators
12
Citations
Publications by NC Obitte
1 publication found • Active 2013-2013
2013
1 publicationPiroxicam Solid Lipid Microparticles: In vitro and in vivo Evaluation
with SA Chime, DC Ibe, OR Nweke, TC Ugwudah
6/1/2013
The aim of this work was to investigate the potential of solid lipid microparticles (SLM) to offer gastroprotection and improve piroxicam’s anti-inflammatory property. The effects of NaCl and cabosil® on the properties of the SLM were also evaluated. The SLM were prepared by the hot homogenization technique using Ultra turrax (T25 Basic digital). Phospholipon® 90G and Capra hircus fat constituted the lipid matrix. The particle size, drug content, encapsulation efficiency, in vitro drug release, anti-inflammatory and ulcerogenic studies were carried out on the formulations. Results showed that carbosil® significantly (p
Author Statistics
Total Publications:1
Years Active:1
First Publication:2013
Latest Publication:2013
Collaborators:4
Citations:12
Collaborators