Mohammed Aslam

Hypertension is the most important risk factor for cardio vascular disease. But, the key question remains: which of the many available types of blood pressure lowering drugs is the better choice as first line medication. Hence, the prospective, randomized, single blind , Comparative study was conducted  at tertiary care Hospital to  assess  the beneficial outcomes of drugs by comparative method. The study concludes that the physicians were prescribed the ACEIs for hypertension with various co morbidities as per JNC-7 guidelines. The study conclude that the A+E+N is the most effective combination therapy for better control of hypertension. The study indicates that the combination therapy can be individualized according to the presence of co morbidities  with  HTN.

  Cucumis melo Linn. (family cucurbitaceae) is extensively cultivated throughout India particularly in the hot and dry North-Western areas. Its fruit pulp, root, seeds and seed oil are used for medicinal purposes. In Unani medicine, the seed kernel is commonly used to treat various disease conditions. Seeds are having diuretic, lithontriptic, laxative, demulcent and refrigerant properties. There are many varieties of melon available and they also show great diversity in foliage. Hence, adultration is very common with this plant. Standardization provides a more reliable, effective and high-quality product by confirming the presence of plant constituents qualitatively and quantitatively. Hence, efforts have been made to standardize the seed to provide scientific data for identification, authentication and distinguishing the plant from its adulterants. The morphological, microscopic, physicochemical and chromatographic studies of Cucumis melo seed will be useful for quality control of this drug in formulations and would serve as a standard reference for further studies. Key words: Adultration, Cucumis melo, flavonoid, phenolic, standardization