Mohammad Aslam

From very beginning, human is very curious about health and its prevention. In every era of world memoirs of life, different definitions and thoughts came under consideration about health. Every civilization, like Babylonians, Egyptians, Greeks and Mesopotamians etc has tried to suggest the best ways for the human achievements of well beingness. Greek physicians in BC century have paved great attention towards this important task in ratiocinative way. They elaborated the concept of health and factors which are essential for its maintenance. Among them, Riyazat (exercise) is the very basic and useful tool for maintenance of health. As well as, other recommendations of exercise have also described by Greek physicians. Unani physicians provided cognitions regarding timing, modes, and benefits of Riyazat. In this review paper, it will be attempted to provide the benefitting 15owledge to the humanity to save the health and promote the cognitive values. Key words: Riyazat; Greek physicians; Health; Humor; Mizaj, Exercise

Peucedanum grande has been found to be associated with the multiple therapeutic properties. In the present study, we have used P. grande as an ameliorating agent against nephrotoxic effects of Mercuric chloride (HgCl2). The rats were given pretreatment of P. grande orally at a dose of 60 and 120 mg/kg body weight for five consecutive days. Mercury chloride 4 mg/kg body .wt was used as renal toxicant, and injected subcutaneously in the neck region in a volume of 1 ml/kg. The modulatory effects of P. grande on HgCl2 induced nephrotoxicity was investigated by assaying oxidative stress biomarkers, lipid peroxidation, serum kidney toxicity markers and by histopathological examination of kidney. The HgCl2 induced nephrotoxicity by depleting antioxidant levels, elevating the level of serum creatinine and BUN, as well as damaging the normal architecture of kidney. P. grande pretreatment prevented deteriorative effects induced by HgCl2 through a protective mechanism that involved reduction of increased oxidative stress as well as by restoration of histopathological change against HgCl2 administration.