Manuja VS

Prostatitis is the inflammation of the prostate gland can be due to an infection as well as other various causes. Prostatitis is a common condition, with 35- 50 % of men affected with symptoms associated with Prostitis during their lifetime. Prostatitis can be caused by bacteria that leak into the prostate gland from the urinary tract. It can also caused by sexually transmitted organism such as Neisseriagonorrhoeae Chlamydiatrachomatis, HIV, Escherichia coli. According to National Institute Of Health Chronic Prostatitis Symptoms (NIH-CPSI) Prostatitis is of three types, Acute bacterial prostatitis, Chronic bacterial prostatitis, Chronic prostatitis /chronic pelvic pain syndrome, A symptomatic inflammation prostatitis .Chronic prostatitis /chronic pelvic pain syndrome is the common condition and most cases of prostatitis fall into this category. Traditionally, Chronic prostatitis /chronic pelvis pain syndrome in men was believed to be related to inflammation (usually secondary to infection) localized to the prostate [1]. Management of chronic prostatitis/chronic pelvic pain syndrome consisted of antibiotics and anti inflammatory and, later ?-blockers and 5 -reductase inhibitors.?-Blockers, antibiotics and combination of these therapies provide greatest improvement in treatment of chronic prostatitis/chronic pelvis pain syndrome. Chronic prostatitis is not a single condition, but a term that is loosely used to describe a group of conditions causing genito –pelvic pain and urinary dysfunction in adult men [10].Both chronic prostatitis and the chronic pelvis pain syndrome is associated with abnormalities in semen and infertility and also result in the reduction in the quality of the life. Prostatitis tissues are best penetrated by drugs with a high pKa and high lipid solubility, such as quinolones ,macrolides ,tetracyclines and sulfa drugs [3]. Antibiotic therapy is recommended for acute exacerbation of chronic prostatitis, chronic bacterial prostatitis and chronic inflammatory prostatitis, if there is clinical, bacteriological or supporting immunological evidence of prostate infection[9]. Antibiotics treatment should be stopped if there is no improvement in symptoms. Many patients  with category III prostatitis will improve with antibiotic therapy.

AIM :Febrile  seizure  is  the  one  of  the  most  common  convulsive  disorders, mainly  occur  following  high  fever  without  any  evidence  of  underlying  health  issues, typically   in  the  children  of  age  of  upto  6  years. The  aim  of  this  study  was  to  assess the  relationship  between  variable  causative  factor  involved  in  the  incidence  of  febrile  convulsions between the  children  referred  to  Cosmopolitan Hospital, Thiruvananthapuram, Kerala (India). This  was  a hospital  based  prospective  observational  study. The  main  purpose  of  this  study  was  to identify  the  relationship  between  variable  risk  factors  associated with febrile  convulsion  in  children. The  children  of  age  upto  6 years  were  studied  to  assess  the  relationship  between  the  types of seizure ,gender ,electrolytes  and  variable  disease  conditions  which  leads  to  the  development  of  convulsive  event  in  children. The age and febrile seizure has a correlation that the children below 3 years is more hospitalized with febrile seizure. Viral fever associated febrile seizure shows more prevalence. Type of seizure and gender do not have any positive correlation in this study. Lab data provide significant positive correlation with the incidence febrile seizure. Pregnancy related complications and antenatal and natel complications also shows a significant relationship to the febrile seizure. Decreased breast feeding in the children also leads to the events of febrile seizure. family history of febrile seizure also provide a major relationship with febrile convu. Risk factor such as age, body temperature, family history, breastfeeding, low birth weight, cesarean, lab data’s that are involved in the development of febrile seizure were identified.