Ch. Manjusri

There is an increasing incidence of cancer not just in our country but worldwide. The aim of this study is to evaluate socio-demographic data, knowledge, awareness, practice level in cancer patients through assessment of their respective attendants. A self-administered, structured, open ended and pretested questionnaire covering the general characteristics, KAP about cancer, screening and treatments was used to collect responses of cancer patient attendants in KIMS a Teaching Hospital at Hyderabad. Their age group was between 18-79years. The educational preparations of the attendants are as follows: 50 attendants are grouped as “CONTROL”, 50 are grouped as “TEST”. The information thus collected was entered and analyzed in SPSS and Microsoft Excel software. Responses from 100 attendants were recorded and analyzed. The results of both groups i.e. TEST and CONTROL pre-post interventions were tabulated and compared between the groups, educational intervention was given to only test group thus paired t-test results obtained at level of significance 0.005, shown that only test group attendants shown significant difference in aspects of knowledge and practice when compared to that of the control group who received information only at the end of the study. Our study has shown that educational interventional study give high scope in comparative studies where pre-post interventions were in use.

Para hydroxyacetophenones react with different aldehydes of Para nitro benzaldehyde (Ia) ,Ortho nitro  benzaldehyde (Ib),4 hydroxy 3methoxy benzaldehyde (Ic) , 3, 4 dimethoxybenzaldehyde (Id)  in the presence of aqueous solution of potassium hydroxide and ethanol at room temperature to form 1,3 Diaryl-2-propane-1-ones or chalcones. The synthesized compounds were characterized by means of their IR spectral data. All the compounds were tested for their antibacterial activities by the cup plate method on E.coli ,Pseudomonasaeurgenosa, staphylococcus aeureous .Screening results shows that Id compound shows better antimicrobial activity against E.coli