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American Journal of PharmTech Research

C.Manasa

Author Profile
1
Publications
1
Years Active
4
Collaborators
49
Citations

Publications by C.Manasa

1 publication found • Active 2016-2016

2016

1 publication

Synthesis and Evaluation of New Isatin Derivatives for Cytotoxic and Antioxidant Activities

with B.Vineela, K. Blessi Priyanka, T.Kalyani, G.Sammaiah
2/1/2016

In the present study N-(2-oxosubstitutedindolin-3-ylidine)-2-phenylacetohydrazides (IV a-h) have been synthesized in good yields and characterized by IR, PMR and mass spectral analyses. Compounds were evaluated for their preliminary in vitro cytotoxic activity against HeLa cancer cell lines by standard MTT assay and also were screened for antioxidant activity by DPPH method. Our results shown that two of the analogues IVf and IVc  are potent antioxidant agents and IVb and IVg are potent cytotoxic agents.

Author Statistics
Total Publications:1
Years Active:1
First Publication:2016
Latest Publication:2016
Collaborators:4
Citations:49
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