C. D. Upasani
Publications by C. D. Upasani
2 publications found • Active 2020-2020
2020
2 publicationsA Review on Long-circulatory Liposome and Magic Bullet Concept
The long circulatory liposome means shows action towards target organ longer period of time. Liposome are the concentric bilayer in which aqueous volume entirely envelope by the lipid bilayer used to transfer enzymes, protein and drugs to targets cancer cell or tissue. These are chemical moieties in which action towards target organ. It was first discovered by 1965 and soon was proposed drug delivery system. There are numerous application like anti fungal, anti cancer, anti inflammatory and anesthetic drugs. The magic bullet concept of Poul-Ehrlich et al; through very late, offers a logical solution to the age old problem unrelated and unwanted effect of therapeutic agent and optimizing the drug therapy in its true sense. The controlled, sustained and controlled drug delivery can be considered as the magic bullet concept. The long circulatory liposome gives the stealth effect called as killer bomber to cancer cell and arrest the Mitosis of M-phase and G-phase.
A Review on Stability Development Guidelines and Impurities Profile Consideration in Solid Oral Dosage Form
In the pharmaceutical industry an impurity is considered, defined the any other organic material besides the drug substance or pharmaceutical ingredients. Â The impurity may be formed during the formulation or upon aging of two APIs in medicines. Stability testing is an integral part of pharmaceutical development. The primary purpose of stability testing is to provide supporting evidence on stability behavior of pharmaceutical drug products. Stability is the capacity of a drug product to remain within specifications established to ensure its identity, strength, quality and purity.
