Agasa Ramu Mahesh

A series of 2-(Bis(2-chloroethyl)amino)-N-(4-((3-oxobenzofuran-2(3H)-ylidene)methyl) phenyl)acetamide derivatives were synthesized by fusing aurones with nitrogen mustards. Aurones being synthesized by treating 4-nitrobenzaldehydes with various derivatives of 1-(2-hydroxyphenyl)ethenone. The characterization of the synthesized compounds was done by FTIR, 1H NMR and LCMS spectral studies. The titled compounds were tested for their possible anticancer activities by in vitro methods by SRB Assay.  These compounds were found to exhibit a moderate anticancer activity.