Synthesis, Characterization of Novel E-3- (Phenyl)-2-(Phenyl) Prop-2-Enoic Acid Derivatives

A series of novel E-3- (phenyl)-2-(phenyl) prop-2-enoic acid derivatives (1a-1h and 2a-2e) have been synthesized by the base-catalyzed condensation of phenylacetic acids (1) with aryl aldehyde in the presence of triethylamine gave the series of E-3- (phenyl)-2-(phenyl) prop-2-enoic acid (1a-1h). Reaction of thionyl chloride with the E-3- (phenyl)-2-(phenyl) prop-2-enoic acid in benzene under refluxing gave the corresponding acid chlorides, which on subsequent reaction with appropriate amines, and (dialky1amino) ethanol gave compounds 2a-2e the yield of compound was found to be in the range of 60-85%.The synthesized compounds were characterized by their physiochemical properties like solubility, melting point, IR spectroscopy, 1H NMR spectroscopy, Fab MASS and elemental analysis.