mail
editor@ajptr.com
whatsapp
9409046853
logo

American Journal of PharmTech Research

📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

August 2024 Issue 4

Volume 14, Issue 4 - $2024

Volume 14 Issue 4 Cover

Issue Details:

Volume 14 Issue 4
Published:Invalid Date

Editorial: August 2024 Issue 4

Welcome to the 2024 issue of American Journal of PharmTech Research. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr Hemangi J Patel
Editor-in-Chief
American Journal of PharmTech Research

Articles in This Issue

Showing 4 of 4 articles
Research PaperID: AJPTR144001

Curcuma Longa Extract Increases Growth of Salmonella Group of Species

Isha Majumdar, Bhaskar Narayan Chaudhuri, Partha Guchhait, Jeegisha Verma, Ahana Talukdar, Arup Kumar Dawn, Satadal Das

Curcuma longa is a widely used plant in folk medicine. In this study, we assessed the action of the ethanolic extract of C. longa on WHO strains of Salmonella enterica serotype Typhi and Salmonella enterica serotype Enteritidis. Curcumin is one of the most active ingredients of C. longa. In the presence of the ethanolic extract of C. longa, the bacterial count of both Salmonella was remarkably increased which was statistically highly significant. We also could not demonstrate MIC value even at 50 mg/ml concentration of the extract in Salmonella enterica serotype Typhi, while Salmonella enterica serotype Enteritidis only showed MIC value at a very high concentration of 6.25 mg/ml. However, two common bacteria E. coli and Staphylococcus aureus showed a MIC value of 0.39 and 3.125 mg/ml respectively. Thus, the use of C. longa in materials for public use should be done cautiously.

Curcuma longaCurcuminantimicrobial actionminimum inhibitory concentrationSalmonella entericaserotype TyphiSalmonella entericaserotype Enteritidis.
341,458 views
102,426 downloads

Contributors:

 Isha Majumdar
,
 Bhaskar Narayan Chaudhuri
,
 Partha Guchhait
,
 Jeegisha Verma
,
 Ahana Talukdar
,
 Arup Kumar Dawn
,
 Satadal Das
Research PaperID: AJPTR144002

A Study On Common Animal Husbandry and Hygiene Practices Among Dairy Cattle Breeding Farmers

V.Sastry Ch, S.V.M.Vardhan, V Bhaskara Reddy

The objective of this work was to develop, use and present a detailed questionnaire for the evaluation of health management in dairy small ruminants; it includes the questions organized in five sections: Socio Economic conditions (general), Feeding Management, Financial Participation, Breeding of milk animals and Health care & Livestock Management. In this study a adoption level of scientific dairy farming practices by dairy farmers of study region, the dairy farmers who were the regular members of Milk Producers’ for the last 3 to 5 Years.  In this study 80% of small and medium Live stock holders. The experience of the investigator, the primary language of farmers and asking clarifications by the farmers affected the duration of the interview. In accord with the needs of a particular study, it can be modified, by adding more specific questions or omitting others deemed of less importance. Moreover, it can also be used for routine monitoring purposes, as a useful means to record.  To the best of our knowledge, the questionnaire is the most extensive and detailed one available internationally for dairy small ruminants.

Livestockanimal husbandrysmall scale farmercalf managementfield studyhealth management+4 more
341,579 views
102,463 downloads

Contributors:

 V.Sastry Ch
,
 S.V.M.Vardhan
,
 V Bhaskara Reddy
Research PaperID: AJPTR144003

Development and Validation of RP HPLC Method For the Simultaneous Estimation of Bilastine and Montelukast Tablet Formulation

Dipika. G. Itnare, Sachin S. Rane, Rajesh Y. Chaudhari

A new simple, rapid, precise and accurate assay method was developed for simultaneous estimation of Bilastine and Montelukast in pure form and tablet form. The analytes were separated by RP HPLC on a RP-Purosnosphere C18 column (5 µm, 4.6mm* 250 mm).The mobile phase was Acetonitrile: water: methanol (30:25:45 v/v) at 1.1 ml/min flow rate satisfactorily resolve the tertiary mixture. The UV detector was operated at 214 nm for the determination of all the drugs. Linearity, accuracy and precision were found to be acceptable over the concentration ranges of 10-50 µg/ml for Bilastine and 5-25 µg/ml for Montelukast with a R2 0.9960 and 0.9974 values respectively. The optimized methods proved to be specific, robust and accurate for the quality control of drugs in bulk drug and pharmaceutical formulations.

BilastineMontelukast sodiumICHValidation etc.
341,719 views
102,582 downloads

Contributors:

 Dipika. G. Itnare
,
 Sachin S. Rane
,
 Rajesh Y. Chaudhari
Research PaperID: AJPTR144004

Browning of Apple Can Prevent Growth of Candida Species

Ahana Talukdar, Bhaskar Narayan Chaudhuri, Partha Guchhait, Isha Majumdar, Jeegisha Verma, Arup Kumar Dawn, Satadal Das

Polyphenol oxidase(PPO) is a food enzyme which holds a very important place in the food industry mainly because of its impairing effects. This enzyme leads to the darkening of tissue when fruits are cut or any damage occurs which leads to the depreciation of nutritional value and food acceptability. It is not clear which roles this compound may have in cell metabolism. In plants, PPO contributes to defence mechanisms against pests and pathogens by producing toxic quinones that deter herbivory and inhibit microbial growth. In this report, the possible antifungal effects were examined. Analyses are carried out by properties of standard polyphenolic substances oxidized by PPO were assayed on Red delicious apple extract whose phenolics were previously isolated.

Polyphenol oxidaseantifungal activityRed delicious appleminimum inhibitory concentrationCandida albicansCandida parapsilosis
341,822 views
102,612 downloads

Contributors:

 Ahana Talukdar
,
 Bhaskar Narayan Chaudhuri
,
 Partha Guchhait
,
 Isha Majumdar
,
 Jeegisha Verma
,
 Arup Kumar Dawn
,
 Satadal Das
Whatsapp