Zackaria Fataftah
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Publications by Zackaria Fataftah
1 publication found • Active 2013-2013
2013
1 publicationSynthesis of Semi-tetracycline Backbone Through Diels-Alder Reaction of 2,3-Dimethylbutadiene or Cyclopentadiene With 1,4-Benzoquinones
with Raad Al-Hamdany, Kanan M. Wahedy
10/1/2013
Two main semi-tetracycline systems were synthesized. The strategy of such synthesis depends on the transformation of aroyl-1,4-benzoquinone to aroylketal-1,4-benzoquinone causes a regiocontrol addition of cyclopentadiene and 2,3-butadiene to the unsubstituted side of the quinone. These ketal adducts were hydrolyzed using the acidic media; as a result deketalization and enolization in one step give the semi-tetracycline system. The structures of these compounds were confirmed by NMR, IR, MS and elemental analysis.
Author Statistics
Total Publications:1
Years Active:1
First Publication:2013
Latest Publication:2013
Collaborators:2
Citations:22
Collaborators