Yedla Anilchowdary
Author Profile
Lamar University, Department of Chemistry, Beaumont, Texas, U.S.A.
1
Publications
1
Years Active
5
Collaborators
16
Citations
Publications by Yedla Anilchowdary
1 publication found • Active 2012-2012
2012
1 publicationDesign and In-Vitro evaluation of human serum albumin loaded Paclitaxel nanosuspension
with AmarnathReddy Ganji, Kiran K Jadhav, Sanjay P Umachigi, Pradeep Shivakumar, Palleti SainathReddy
4/1/2012
At current 40% of the drugs were poorly soluble and were also called as “brick dust”. And the drugs which were belonging to the BCS CLASS II & IV were most eligible for this Nanosuspension technology. Here by using different methods we are reducing the particle size so the surface area will be increases ultimately it leads to increase in the bio availability. This instance was observed mostly in the case of anti-cancer drugs. Paclitaxel with 25% of Human Serum Albumin (HSA) showed very good results in terms of drug content, particle size, zeta potential and %CDR. Key words: Nanosuspension, Paclitaxel, Human Serum Albumin (HSA), High pressure homogenization.
Author Statistics
Total Publications:1
Years Active:1
First Publication:2012
Latest Publication:2012
Collaborators:5
Citations:16
Collaborators