T. Aravinda
Author Profile
Department of Chemistry, Nitte Meenakshi Institute of Technology, Yelahanka, Bangalore-560064, India.
1
Publications
1
Years Active
1
Collaborators
40
Citations
Publications by T. Aravinda
1 publication found • Active 2017-2017
2017
1 publicationAn Efficient One Pot Synthesis of Biologically Active Quinoline Trifluoro Esters and DNA Studies
with M.S. Raghu1and Srilatha Rao
10/1/2017
We deliver chemistry of multicomponent reaction (MCR) for 2-Benzyl-5-(2-benzyloxycarbonylamino-3-Phenyl-propylamino)-4-(2-chloro-quinoline-3yl)-5-(2,2,2-trifluoro acetoxy)-pentanoic acid methyl ester (6a-g) by flexible Ugi multi-component approach, through commercially available amino acid, aldehydes, isocyanides and amino acid ester in one pot. Further, the binding activity with CT DNA and nucleus property with pUC 19 DNA were studied by absorption spectra (Kb constant is= 4.2 × 10-4 M-1). The DNA binding results explored that the new molecule bind to DNA through interaction and also an efficient nucleus agent.
Author Statistics
Total Publications:1
Years Active:1
First Publication:2017
Latest Publication:2017
Collaborators:1
Citations:40
Collaborators