Sowjanya Gummadi

The main purpose of this review is to highlight the importance of colorimetric approaches to drug analysis both in dosage forms as well as biological samples. Colorimetric methods using colorimetric reagents are highly sensitive, specific and an easy way of determining various analytes in a variety of matrices within a short time. The colorimetric procedures discussed are statistically validated and reported in various quality control laboratories. Hence in the present review significance of colorimetric procedures, various reagents used along with principles and applications are mentioned. Key words: Colorimetric approaches, sensitive, matrices, quality control, applications.

Chemometrics is the use of mathematical and statistical methods to improve the understanding of chemical information and to correlate quality parameters or physical properties to analytical instrument data. It is a data-driven multidisciplinary science that allows maximum collection and extraction of useful information from the analytical data of numerous application areas such as chemistry, biochemistry, medicine ,biology and chemical engineering. This review focuses mainly on numerous chemometric models used and their relevant applications in the field of pharmaceutical sciences.