Singh Chandan

The Ebola virus causes an acute, serious illness which is often fatal if untreated. Ebola virus disease (EVD) first appeared in 1976. It is thought that fruit bats of the Pteropodidae family are natural Ebola virus hosts. Ebola is introduced into the human population through close contact with the blood, secretions, organs or other bodily fluids of infected animals such as chimpanzees, gorillas, fruit bats, monkeys, forest antelope and porcupines found ill or dead or in the rainforest. It can be difficult to distinguish EVD from other infectious diseases such as malaria, typhoid fever and meningitis. Prevention is the best treatment: As far as we know, this virus is transmitted through bodily fluids and it is not air borne. If one is not going to contract this virus in flying or sitting next to Ebola infected person, unless come in contact with blood, vomits, stool, urine or get injected with infected needle, then he or she will not affected. Healthy nutrition is the best way to keep immune system boosted. Group of studies and others like them are recognizing the central role of the immune system in survival for an infection like Ebola, which has no apparent clinical cure, natural reinforcement of the immune system may represent an oasis of hope in the desert of fear and panic. Exercise is an important foundation of health. Exercising supports the immune system through its physiological and mechanical effects on the body. Ayurveda is the ancient science of health. The word Ebola is obviously not mentioned in the AtharvaVeda, however, the sign and symptoms that we see today in ebola hemorrhagic fever are the same as the disease called Raktasthiwi Sannipat (Raktasthiwi Sannipat). Rakta means ‘blood’, ‘sthiwan’ means ‘to spit out’, and ‘sannipat’ means the involvement of a different dosha, which is usually a complicated type of disease; difficult to cure and sometimes incurable too. Herbal support is the next line of protection that adds to the benefits of daily activity. Ayurveda offers a wide range of herbs called rasayana. According to the Ayurvedic theory, rasayana herbs are rejuvenative medicines that promote health at all tissue levels of the body. Amla, Emblica officinalis, is one of the more popular rasayana All the above discussion based on Ayurvedic textual references inspires to author to go for further review on treatment of Ebola Virus Disease as well as other fatal diseases with Ayurveda. This will lead to lower morbidity and mortality rate due to many viral or other infective disease. Authors made an attempt to emphasize that the Ayurveda herbs may play a vital role for the treatment / management of EVD.

Ayurveda pharmacopeia is based upon herbal, mineral and herbo-mineral natural products but herbs takes first rank in pharmaceutics.  Herbal medicines have been widely used all over the world since ancient times and have been recognized by physicians and patients for their better therapeutic value as they have fewer adverse effects as compared with modern medicines. Unlike the existing allopathic system, the herbal remedies have hundreds and thousands of constituents that all work together against the diseases. Mostly, the conventional pharmaceuticals or pharmacognostical products in the market are rooted from natural products and their derivatives with herbal products playing pivotal role. All over the world, the research on these herbal remedies has been carried out in the different fields’ for instance pharmaceutical chemistry, pharmacognosy, pharmacology and clinical therapeutics.  ‘Nanotechnology’ is the new emerging technology in the drug discovery and it has the property of self targeting in the sense that without the attachment of a specific legend, these can be used for targeting, due to their distinctively small size, at the infected pathological areas. Some of such formulations are already present in the market and many more are expected to come by 2020 after their success in ongoing clinical trials. Drug delivery research is clearly moving from the micro- to the nanosize scale. Nanotechnology is therefore emerging as a field in medicine that is expected to elicit significant therapeutic benefit. Nanoparticles are able to adsorb and/or encapsulate a drug, thus protecting it against chemical and enzymatic degradation. A nanocarrier is nanomaterial being used as a transport module for another substance, such as a drug. Nanocarriers are currently used in drug delivery and their unique characteristics demonstrate potential use in chemotherapy. Herbal remedies may be selected as feasible drug candidate for delivery through a nano delivery system. It is being assumed that the “herbal remedy” with the nanocarriers will increase its potential for the treatment of various chronic diseases and health benefits. In this review, author has made an effort to explore this new approach is escalating the interest of number of scientists to improve and to accelerate the joint drug discovery and development of novel nano delivery systems for ayurveda herbal remedies.