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American Journal of PharmTech Research

Satyanarayana .T

Author Profile
Browns college of Pharmacy, Khammam, Andhra Pradesh.
1
Publications
1
Years Active
5
Collaborators
39
Citations

Publications by Satyanarayana .T

1 publication found • Active 2011-2011

2011

1 publication

VALIDATED RP-HPLC FOR SIMULTANEOUS ESTIMATION OF SITAGLIPTIN PHOSPHATE AND METFORMIN HYDROCHLORIDE IN TABLET DOSAGE FORM.

with Shyamala.M, Mohideen.S, Ch.NarasimhaRaju, Suresh Kumar.P, Swetha.K
8/1/2011

Rapid and accurate High performance liquid chromatography method is described for Simultaneous estimation of Metformin Hydrochloride and Sitagliptin Phosphate from the combination tablet dosage form. The separation of two drugs was achieved on HYPERSIL (250 x 4mm i.d) 5μ column. The mobile phase consists of Acetonitrile and phosphate buffer in the ratio of 45:55. The detection was carried out at a wavelength 260nm. The method was validated for system suitability, linearity, accuracy, precision, robustness and stability of sample solution. The linear ranges for Metformin Hydrochloride and Sitagliptin Phosphate were 20-120μg/mL, 2-12μg/mL respectively with good recoveries i.e. 99.16% to 99.89%.

Author Statistics
Total Publications:1
Years Active:1
First Publication:2011
Latest Publication:2011
Collaborators:5
Citations:39
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