Ramana BV
Publications by Ramana BV
1 publication found • Active 2017-2017
2017
1 publicationDesign and Development of Immediate Release Tablets Amlodipine Besylate by Employing Modified Superdisintegrants
The aim and objective of the present work is to design and develop fast disintegrating tablets of Amlodipine Besylate to improve the patient compliance and desired bioavailability by selected delivery system by following immediate release mechanism. The drawbacks of the tablets can be overcome using methods involved in modified dissolving tablets, oral dissolving tablets (MDT) or orally disinter grating tablets (ODT) ; which started as an alternative oral dosage forms. To achieve successful delivery of drug , it needs to be protected from degradation, drug release to be improved and increase absorption. For this objective and to have the rapid uptake of drug in solution form by rapid disintegrating formulation to be expected to have better Therapeutic effect of both drugs in the gastrointestinal tract. The research objective  of the present work understands the novel advancements that are made in oral fast disintegration preparations incorporated anti hypertensive drug like Amlodipine Besylate using combination of super disintegrants.
