Nikath Jahan
Author Profile
Department of Pharmaceutical Analysis,Deccan School of Pharmacy, Hyderabad
1
Publications
1
Years Active
3
Collaborators
27
Citations
Publications by Nikath Jahan
1 publication found • Active 2016-2016
2016
1 publicationAnalytical Method Development and Validation for Estimation of Bosentan in Bulk and Tablet Dosage Form by High Performance Thin Layer Chromatography
with S.H.Rizwan, V.Girija Sastry, Shaik Gazi
2/1/2016
A simple, sensitive and accurate method employing HPTLC has been developed and validated as per ICH guidelines for determination of Bosentan in bulk and Tablet dosage form. The absorption maxima of the drug were found to be 288 nm in methanol. The method was validated as per ICH guidelines. The linearity range was found to be 50-300 ng/ml with a regression coefficient of 0.98.Subsequent validation parameters like precision, repeatability in terms of Interday and Intraday precision and recovery studies were evaluated with satisfactory results, the % RSD for these parameters was found to be 1.73%,1.30-0.48%,1.80 – 0.45 % , 1.54 – 1.48 % respectively with an Rf value of 0.23.
Author Statistics
Total Publications:1
Years Active:1
First Publication:2016
Latest Publication:2016
Collaborators:3
Citations:27
Research Topics
Collaborators