Modi Vishal S

Green Chemistry covers analysis of sample containing organic compounds in different composition of matrices by using gas chromatography or liquid chromatography method with the use of less toxic solvents. It is important that the methods used for analysis of analyte in a sample have negligible harmful environmental impact. Green Chromatography mainly focus on making the methods greener during analysis at all the steps, starting from collection of sample, to its preparation and then its separation and finally determination of analyte. The present review includes the goals to achieve green chromatography using environmentally benign solvents and reagents, most recent contribution in the development of greener sample preparation since it has effect on whole analytical methodology, chromatographic separation techniques, advantages of Green Chromatography, Green micro extraction techniques (solid phase micro extraction, still bar sorptive, liquid phase micro extraction) is included with special attention. The approach in making chromatographic separations greener differs depending on the type of chromatography which includes solvent less extraction technique- aiming to eliminate or reduce the amount of organic solvents consumed without loss in chromatographic performance. In gas chromatography it is advisable not to use helium as the carrier gas because it is a non-renewable resource. GC separations using low thermal mass technology can be considered greener as energy consumption is minimized by this technology. In liquid chromatography the focus will be on the reduction of solvent consumption and replacement of toxic and environmentally hazardous organic solvents with more benign alternatives.